Neova Biogene

TREXOVA1g

Download prescription safety &
information

TREXOVA1g

Download prescription safety &
information

TREXOVA 1g

Download prescription safety &
information

Trexova 1g Injection

Prescription Required

Manufacture

Salt Composition

Methotrexate (1g)

Storage

Store below 30°C.
Methotrexate 1g

Trexova 1g Injection

Prescription Required

Manufacture

Salt Composition

Methotrexate (1g)

Storage

Store below 30°C.

Methotrexate 1g
Methotrexate 1g

Trexova 1g Injection

Prescription Required

Manufacture

Salt Composition

Methotrexate (1g)

Storage

Store below 30°C.

Information of Trexova Methotrexate 1g

Trexova  Methotrexate 1g  is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy.
 
Trexova  Methotrexate 1g Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.
Trexova  Methotrexate 1g may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
 
The most common side effects of Trexova  Methotrexate 1g Injection include: nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor.
There may be ways of preventing or reducing these effects. Trexova Methotrexate 1g is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.
 
Before taking Trexova  Methotrexate 1g Injection, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
 
TREXOVA Methotrexate 1g medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations, both before and during treatment with this medicine.

Indication of Trexova Methotrexate 1g Injection

Trexova  Methotrexate 1g is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole.
  • In acute lymphocytic leukemia, Trexova  Methotrexate 1g is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia.
  • Trexova  Methotrexate 1g is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stage non-Hodgkin’s lymphomas.
  • Trexova  Methotrexate 1g in high doses followed by leucovorin rescue in combination with other chemotherapeutic agents is effective in prolonging relapse-free survival in patients with non-metastatic osteosarcoma who have undergone surgical resection or amputation for the primary tumor.
  • Trexova  Methotrexate 1g is indicated in the symptomatic control of severe, recalcitrant, disabling psoriasis that is not adequately responsive to other forms of therapy, but only when the diagnosis has been established, as by biopsy and/or after dermatologic consultation.

Benefits of Trexova Methotrexate 1g Injection

In Cancer:  
Trexova Methotrexate 1g Injection belongs to a group of medicines called antimetabolites and is referred to as a cytotoxic. It works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
 
In Treatment of Rheumatoid arthritis:
Trexova Methotrexate 1g Injection belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body’s immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.
 
In Treatment of Psoriasis:
Trexova Methotrexate 1g Injection belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly.
 
Trexova Methotrexate 1g works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO not take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects of Trexova Methotrexate 1g Injection

Before you start Trexova Methotrexate, your doctor will need to make sure it is the right drug for you by checking if:
  • you’re pregnant or planning a family
  • you’re breastfeeding
  • you have an infection
  • you have a liver or kidney disease
  • you’ve had a recent vaccination
  • you’ve had severe mouth ulcers
  • you’ve had ulcers in the stomach or bowel
Trexova Methotrexate  Injection can sometimes cause side effects, which may include:
  • feeling sick
  • headaches
  • vomiting
  • Diarrhea
  • shortness of breath
  • mouth ulcers
  • minor hair loss and hair thinning
  • Rashes.
How To Use Trexova Methotrexate ?
Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Trexova Methotrexate 1g Injection Works

Methotrexate is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.

Safety Advice For Trexova Methotrexate 1g

1

Alcohol

CAUTION

Caution is advised when consuming
Alcohol with Trexova Methotrexate . Please consult your doctor.
pregnancy

Pregnancy

UNSAFE

Trexova Methotrexate  is highly unsafe during pregnancy .Seek your doctor’s advice as studies on pregnant woman and animals have shown significant harmful effects to the developing baby.
2

Breast Feeding

UNSAFE

Trexova Methotrexate  is unsafe to use during breastfeeding.
Data suggests that the drug may cause toxicity to the baby.
3

Driving

UNSAFE

Trexova Methotrexate may decrease alertness, affects your vision or make you feel sleepy and dizzy. Do not drive if these symptoms.
4

Kidney

CAUTION

Trexova Methotrexate  should be used with caution in patients with kidney disease.Dose
adjustment of Methocel 1000mg injection may be needed.Please consult your doctor.Regular monitoring of kidney function test is adviced while you are taking this medicine.
5

Liver

CAUTION

Trexova Methotrexate should be used with caution in patients with Liver disease. Dose
Adjustment of Methocel 1000mg injection may be needed. Please consult your doctor. Use of Methocel 1g injection is not recommended in patients with severe liver disease.
1

Alcohol

CAUTION

Caution is advised when consuming
Alcohol with Trexova Methotrexate . Please consult your doctor.
pregnancy

Pregnancy

UNSAFE

Trexova Methotrexate is highly unsafe during pregnancy .Seek your doctor’s advice as studies on pregnant woman and animals have shown significant harmful effects to the developing baby.
2

Breast Feeding

UNSAFE

Trexova Methotrexate  is unsafe to use during breastfeeding.
Data suggests that the drug may cause toxicity to the baby.
3

Driving

UNSAFE

Trexova Methotrexate  may decrease alertness, affects your vision or make you feel sleepy and dizzy. Do not drive if these symptoms.
4

Kidney

CAUTION

Trexova Methotrexate  should be used with caution in patients with kidney disease.Dose
adjustment of Methocel 1000mg injection may be needed.Please consult your doctor.Regular monitoring of kidney function test is adviced while you are taking this medicine.
5

Liver

CAUTION

Trexova Methotrexate  should be used with caution in patients with Liver disease. Dose
Adjustment of Methocel 1000mg injection may be needed. Please consult your doctor. Use of Methocel 1g injection is not recommended in patients with severe liver disease.
1

Alcohol

CAUTION
Caution is advised when consuming
Alcohol with Trexova Methotrexate . Please consult your doctor.
pregnancy

Pregnancy

UNSAFE
Trexova Methotrexate is highly unsafe during pregnancy .Seek your doctor’s advice as studies on pregnant woman and animals have shown significant harmful effects to the developing baby.
2

Breast Feeding

UNSAFE
Trexova Methotrexate  is unsafe to use during breastfeeding.
Data suggests that the drug may cause toxicity to the baby.
3

Driving

UNSAFE
Trexova Methotrexate may decrease alertness, affects your vision or make you feel sleepy and dizzy. Do not drive if these symptoms.
4

Kidney

CAUTION
Trexova Methotrexate should be used with caution in patients with kidney disease.Dose
adjustment of Methocel 1000mg injection may be needed.Please consult your doctor.Regular monitoring of kidney function test is adviced while you are taking this medicine.
5

Liver

CAUTION
Trexova Methotrexate should be used with caution in patients with Liver disease. Dose
Adjustment of Methocel 1000mg injection may be needed. Please consult your doctor. Use of Methocel 1g injection is not recommended in patients with severe liver disease.

Links To Clinical Trial Paper (Only For Physician)

For any other information